Author and year Study Resource used Treatment Objective 1 Alban. (2023) Multisensory module for cognitive development in children with prefrontal lesions Intelligent module Cognitive stimulation 2 Ruiz, EAA, & Ruiz, RSA (2023). Digital ecosystem for multisensory stimulation in children with Down syndrome. Digital ecosystem Multisensory stimulation 3 Córdova, JPA, Velez, APM, & Guanoluisa, KAM (2024). Playful virtual reality in visual and cognitive training in children with Down syndrome. Virtual reality Visual and cognitive training 4 . Pacheco Pozo, MPE DOWN IN THE AQUATIC ENVIRONMEN T. (2024). Equine therapy to develop psychomotor skills in preschool children with Down syndrome. Equine therapy Psychomotor skills 5 Pasto Yanchatipan, AI (2024). Respiratory physiotherapy in patients with Down syndrome (Bachelor's thesis, Riobamba, National University of Chimborazo). Breathing exercises Respiratory system 6 Madrid Concha, J. (2024). Methods for training students with Down syndrome in the aquatic environment Aquatic environment Aquatic therapy 7 Murga Lemus, JR (2025). Literature review of the therapeutic benefits of eccentric exercise as a treatment to improve muscle strength in patients with Down syndrome aged 10 to 15 years The eccentric exercise Muscle strength 8 Reynoso, M., & Adarmí, G. (2025). Literature review of the therapeutic benefits of the Bobath method in psychomotor delay in patients with Down syndrome aged 0-10 years (Doctoral dissertation). Bobath Method Psychomotor Development